The forced degradation products of a given formulation will be generated using Zeneth. These will include degradants of the active molecules and excipients and the reactive derivatives of any of the shared components with other molecules in the formulation.
The assessment will contain the following details for each degradant:
1. Transformation mechanism
2. Reactants
3. Intermediates if any
4. Triggers for the reaction
5. Likelihood of the transformation occurring.